Santhi W S

Education

• Doctor of Philosophy, Regional Cancer Centre, University of Kerala – 2010
• Master of Science, MG College, University of Kerala – 2001
• Bachelor of Science, Govt. College for Women, University of Kerala – 1991

Research Experience

• Ph.D work entitled ‘TUMOR PROGRESSION MINIMAL RESIDUAL DISEASE AND NUCLEAR FACTOR KAPPA B IN ORAL CANCER’.

Research Interests

• Evaluation of Molecular Markers in tumour progression
• Production of bio-ethanol from bio-waste.

Teaching Experience

• Working as Assistant Professor in the Post Graduate Department of Botany and Biotechnology, Bishop Moore College, Mavelikara, Kerala, India, since 22nd September 2010.

Publications in Peer Reviewed Journals

• Ambili R, Santhi WS, Janam P, Nandakumar K, Pillai MR. Expression of activated transcription factor nuclear factor-kappaB in periodontally diseased tissues. J Periodontol. 2005; 76(7):1148-1153.
• Santhi WS, Sebastian P, Varghese BT, Prakash O, Pillai MR. NF-kappaB and COX-2 during oral tumorigenesis and in assessment of minimal residual disease in surgical margins. Exp Mol Pathol. 2006; 81(2):123-130.
• Rajendran R, Rajeesh MP, Shaikh S, Shanthi, Pillai MR. Expression of matrix metalloproteinases (MMP-1, MMP-2 and MMP-9) and their inhibitors (TIMP-1 and TIMP-2) in oral submucous fibrosis. Indian J Dent Res. 2006; 17(4):161-166.
• Pandey M, Prakash O, Santhi WS, Soumithran CS, Pillai RM. Overexpression of COX-2 gene in oral cancer is independent of stage of disease and degree of differentiation. International journal of oral and maxillofacial surgery. 2008;37(4):379-383.
• Santhi WS, Pillai MR. Molecular markers in the identification of potentially malignant lesions and minimal residual disease in oral cavity. Kerala Dental Journal. 2010; 33:11-15.
• Reshmi G, Chandra SS, Babu VJ, Babu PS, Santhi WS, Ramachandran S, Lakshmi S, Nair AS, Pillai MR. Identification and analysis of novel microRNAs from fragile sites of human cervical cancer: Computational and experimental approach. Genomics. 2011. 97:333-40.
• Reshmi G, Ramachandran S, Jissa VT, Babu S.S, Preethi N., Santhi WS, Jayaprakash PG, Pillai MR. C–T variant in a miRNA target site of BCL2 is associated with increased risk of human papilloma virus related cervical cancer—An in silico approach. Genomics. 2011. 98(3):189-93.
• Santhi WS, Prathibha R, Charles S, Anurup KG, Reshmi G, Ramachandran S, Jissa VT, Sebastian P, Radhakrishna Pillai M. Oncogenic microRNAs as biomarkers of oral tumorigenesis and minimal residual disease. Oral Oncol. 2013. S1368-8375(13)00007-9

Publications in Seminar/Workshop Proceedings

• Santhi W.S and M. Radhakrishna Pillai. NF-kappaB and COX-2 in oral surgical margins and assessment of minimal residual disease. International Workshop on Cervical Cancer, NCBS, Bangalore, India. November 2004.
• Santhi W.S, Paul Sebastian and M. Radhakrishna Pillai. Assessment of minimal residual disease in oral cancer patients. International Conference on Biotechnology and Neurosciences, Cochin University of Science and Technology, Cochin, India. December 2004.
• Santhi W.S, Paul Sebastian and M. Radhakrishna Pillai. Expression of NF-kappaB and COX-2 during oral tumorigenesis and in assessment of minimal residual disease in surgical margins. 24th Annual Convention of Indian Association for Cancer Research & International Symposium on Human Papillomavirus and Cervical Cancer, Institute of Cytology & Preventive Oncology, Noida, India, February 2005.
• Santhi W. S, Paul Sebastian, Bipin T. Varghese, Om Prakash and M. Radhakrishna Pillai. NF-appaB and COX-2 during oral tumorigenesis and in assessment of minimal residual disease in surgical margins. Oral Caner Conference, Thiruvananthapuram, India. January 2006.
• Santhi W. S, Sona Charlesa, Paul Sebastiana, G. Reshmia, Surya Ramachandrana, V.T. Jissaa and M. Radhakrishna Pillai. Oncogenic MicroRNAs as Molecular Signature of Oral Tumorigenesis and Minimal Residual Disease. International Conference on Advances in Biological Sciences, Kannur, India. March 2012.
• Participated in the 25th Mid Year Meeting of the Academy of Sciences jointly organised by Indian Academy of Sciences, Indian National Science Academy and The National Academy of Sciences, India, held on 4th and 5th July at Bangalore.

Invited Talks

• Delivered a talk on “Biotechnology – A brief outline” at Peet Memorial Training College, Mavelikara, in connection with Faculty Enrichment and student Empowerment Programme jointly organised by The Board of Education CSI Madhya Kerala Diocese and on Peet Memorial Training College, Mavelikara, on 9th November 2012.

Positions/Responsibilities held

• Academic Council member (2012-2016)

Personal Details

• Date of Birth - 16‐ 5‐1979
• Nationality - Indian